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Functional Ser205Leu polymorphism of the nerve growth factor receptor (NGFR) gene is associated with vagal autonomic dysregulation in humans

Evidence indicates that reduced cardiac vagal (parasympathetic) tone, a robust cardiovascular risk factor, is a trait vulnerability marker of major depressive disorder (MDD). The Ser205/Ser205 genotype of the functional polymorphism (Ser205Leu) of the nerve growth factor receptor (NGFR), also called...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chang, Chuan-Chia, Fang, Wen-Hui, Chang, Hsin-An, Huang, San-Yuan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538378/
https://ncbi.nlm.nih.gov/pubmed/26278479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13136
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