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Plk1 regulates MEK1/2 and proliferation in airway smooth muscle cells

BACKGROUND: Polo-like kinase 1 (Plk1) is a serine/threonine protein kinase that has been implicated in the regulation of mitosis. In addition, the activation of mitogen-activated protein kinase (MAPK) is a key event in the early stage of the growth factor response. The role of Plk1 in MAPK phosphory...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Jiang, Sixin, Tang, Dale D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531535/
https://ncbi.nlm.nih.gov/pubmed/26242183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0257-8
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