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Pak2 links TCR signaling strength to the development of regulatory T cells and maintains peripheral tolerance
Although significant effort has been devoted to understanding the thymic development of Foxp3+ regulatory T cells (Tregs), the precise signaling pathways that govern their lineage commitment still remain enigmatic. Our findings show a novel role for the actin-cytoskeletal remodeling protein, P21-act...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530067/ https://ncbi.nlm.nih.gov/pubmed/26157175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500843 |
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