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Pak2 links TCR signaling strength to the development of regulatory T cells and maintains peripheral tolerance

Although significant effort has been devoted to understanding the thymic development of Foxp3+ regulatory T cells (Tregs), the precise signaling pathways that govern their lineage commitment still remain enigmatic. Our findings show a novel role for the actin-cytoskeletal remodeling protein, P21-act...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Immunol
मुख्य लेखकों: O’Hagan, Kyle Leonard, Choi, Jinyong, Pryshchep, Olga, Chernoff, Jonathan, Phee, Hyewon
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530067/
https://ncbi.nlm.nih.gov/pubmed/26157175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500843
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