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Inhibitory effects of EGb761 on the expression of matrix metalloproteinases (MMPs) and cartilage matrix destruction

Cytokines such as tumor necrosis factor alpha (TNF-α)-induced expression of matrix metalloproteinase (MMP) play a pivotal role in the destruction of articular cartilage in patients who are suffering from osteoarthritis (OA). Collagen type II, the basis for articular cartilage, can be degraded by MMP...

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Bibliografiske detaljer
Udgivet i:Cell Stress Chaperones
Main Authors: Wang, Xuewen, Zhao, Xingshen, Tang, Shusen
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529858/
https://ncbi.nlm.nih.gov/pubmed/26045200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-015-0600-5
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