Selective inhibition of SIN3 corepressor with avermectins as a novel therapeutic strategy in triple negative breast cancer

Triple negative breast cancers (TNBC) lacking estrogen, progesterone and HER2 receptors account for 10–20% of breast cancer and are indicative of poor prognosis. The development of effective treatment strategies therefore represents a pressing unmet clinical need. We previously identified a molecula...

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發表在:Mol Cancer Ther
Main Authors: Kwon, Yeon-Jin, Petrie, Kevin, Leibovitch, Boris A., Zeng, Lei, Mezei, Mihaly, Howell, Louise, Gil, Veronica, Christova, Rossitza, Bansal, Nidhi, Yang, Shuai, Sharma, Rajal, Ariztia, Edgardo V., Frankum, Jessica, Brough, Rachel, Sbirkov, Yordan, Ashworth, Alan, Lord, Christopher J., Zelent, Arthur, Farias, Eduardo, Zhou, Ming-Ming, Waxman, Samuel
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529816/
https://ncbi.nlm.nih.gov/pubmed/26078298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0980-T
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