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Mannosamine, a novel inhibitor of glycosylphosphatidylinositol incorporation into proteins.

Mannosamine (2-amino-2-deoxy D-mannose) is shown here to block the incorporation of glycosylphosphatidylinositol (GPI) into GPI-anchored proteins. The amino sugar drastically reduced the surface expression of a recombinant GPI-anchored protein in polarized MDCK cells, converted this apical membrane-...

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Main Authors: Lisanti, M P, Field, M C, Caras, I W, Menon, A K, Rodriguez-Boulan, E
格式: Artigo
語言:Inglês
出版: 1991
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC452876/
https://ncbi.nlm.nih.gov/pubmed/1829673
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