Transfection of brain capillary endothelial cells in primary culture with defined blood–brain barrier properties

BACKGROUND: Primary brain capillary endothelial cells (BCECs) are a promising tool to study the blood–brain barrier (BBB) in vitro, as they maintain many important characteristics of the BBB in vivo, especially when co-cultured with pericytes and/or astrocytes. A novel strategy for drug delivery to...

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Détails bibliographiques
Publié dans:Fluids Barriers CNS
Auteurs principaux: Burkhart, Annette, Thomsen, Louiza Bohn, Thomsen, Maj Schneider, Lichota, Jacek, Fazakas, Csilla, Krizbai, István, Moos, Torben
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527128/
https://ncbi.nlm.nih.gov/pubmed/26246240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-015-0015-9
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