Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial

BACKGROUND: Metabolic acidosis is more common with advancing chronic kidney disease, and has been associated with impaired physical function, impaired bone health, accelerated decline in kidney function and increased vascular risk. Although oral sodium bicarbonate is widely used to correct metabolic...

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Dettagli Bibliografici
Pubblicato in:Trials
Autori principali: Witham, Miles D., Band, Margaret M., Littleford, Roberta C., Avenell, Alison, Soiza, Roy L., McMurdo, Marion E. T., Sumukadas, Deepa, Ogston, Simon A., Lamb, Edmund J., Hampson, Geeta, McNamee, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Study Protocol
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522127/
https://ncbi.nlm.nih.gov/pubmed/26231610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-015-0843-6
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