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Suppression of PGC-1α is critical for reprogramming oxidative metabolism in renal cell carcinoma
Long believed to be a byproduct of malignant transformation, reprogramming of cellular metabolism is now recognized as a driving force in tumorigenesis. In clear cell renal cell carcinoma (ccRCC) frequent activation of HIF-signaling induces a metabolic switch that promotes tumorigenesis. Here we dem...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518559/ https://ncbi.nlm.nih.gov/pubmed/26119730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.006 |
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