Increased SHP-1 expression results in radioresistance, inhibition of cellular senescence, and cell cycle redistribution in nasopharyngeal carcinoma cells

BACKGROUND: Radioresistance is the main limit to the efficacy of radiotherapy in nasopharyngeal carcinoma (NPC). SHP-1 is involved in cancer progression, but its role in radioresistance and senescence of NPC is not well understood. This study aimed to assess the role of SHP-1 in the radioresistance...

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Bibliographic Details
Published in:Radiat Oncol
Main Authors: Sun, Ziyi, Pan, Xiaofen, Zou, Zhenwei, Ding, Qian, Wu, Gang, Peng, Gang
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517406/
https://ncbi.nlm.nih.gov/pubmed/26215037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0445-1
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