Scap is required for sterol synthesis and crypt growth in intestinal mucosa

SREBP cleavage-activating protein (Scap) is an endoplasmic reticulum membrane protein required for cleavage and activation of sterol regulatory element-binding proteins (SREBPs), which activate the transcription of genes in sterol and fatty acid biosynthesis. Liver-specific loss of Scap is well tole...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Lipid Res
Egile Nagusiak: McFarlane, Matthew R., Cantoria, Mary Jo, Linden, Albert G., January, Brandon A., Liang, Guosheng, Engelking, Luke J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513997/
https://ncbi.nlm.nih.gov/pubmed/25896350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M059709
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