14-3-3ζ deficient mice in the BALB/c background display behavioural and anatomical defects associated with neurodevelopmental disorders

Sequencing and expression analyses implicate 14-3-3ζ as a genetic risk factor for neurodevelopmental disorders such as schizophrenia and autism. In support of this notion, we recently found that 14-3-3ζ(−/−) mice in the Sv/129 background display schizophrenia-like defects. As epistatic interactions...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Xu, Xiangjun, Jaehne, Emily J., Greenberg, Zarina, McCarthy, Peter, Saleh, Eiman, Parish, Clare L., Camera, Daria, Heng, Julian, Haas, Matilda, Baune, Bernhard T., Ratnayake, Udani, Buuse, Maarten van den, Lopez, Angel F., Ramshaw, Hayley S., Schwarz, Quenten
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513550/
https://ncbi.nlm.nih.gov/pubmed/26207352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12434
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