Pre-administration of turmeric prevents methotrexate-induced liver toxicity and oxidative stress

BACKGROUND: Methotrexate (MTX) is an antimetabolite broadly used in treatment of cancer and autoimmune diseases. MTX-induced hepatotoxicity limits its application. We investigated hepatoprotective effects of turmeric in MTX-induced liver toxicity. METHODS: All experiments were performed on male Wist...

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Pubblicato in:BMC Complement Altern Med
Autori principali: Moghadam, Adel Rezaei, Tutunchi, Soheil, Namvaran-Abbas-Abad, Ali, Yazdi, Mina, Bonyadi, Fatemeh, Mohajeri, Daryoush, Mazani, Mohammad, Marzban, Hassan, Łos, Marek J., Ghavami, Saeid
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511036/
https://ncbi.nlm.nih.gov/pubmed/26199067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-015-0773-6
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