A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo

Notochord-derived Sonic Hedgehog (Shh) is essential for dorsoventral patterning of the overlying neural tube. Increasing concentration and duration of Shh signal induces progenitors to acquire progressively more ventral fates. We show that Notch signalling augments the response of neuroepithelial ce...

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Bibliografische gegevens
Gepubliceerd in:Development
Hoofdauteurs: Stasiulewicz, Magdalena, Gray, Shona D., Mastromina, Ioanna, Silva, Joana C., Björklund, Mia, Seymour, Philip A., Booth, David, Thompson, Calum, Green, Richard J., Hall, Emma A., Serup, Palle, Dale, J. Kim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510595/
https://ncbi.nlm.nih.gov/pubmed/25995356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.125237
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