High-dose methotrexate plus temozolomide as a salvage treatment in metastatic central nervous system Lymphoma: two cases report and review of literature

Temozolomide (TMZ), an alkylating agent, is widely used for treating high-grade gliomas and has emerged as a treatment option for primary central nervous system lymphoma (PCNSL) because of its good penetration of the blood-brain barrier (BBB) and mild toxicity profile. To our knowledge, the role of...

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Bibliographic Details
Published in:Int J Clin Exp Med
Main Authors: Xu, Gaixiang, Yang, Min, Tong, Hongyan, Mao, Liping, Jin, Jie
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509343/
https://ncbi.nlm.nih.gov/pubmed/26221398
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