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Cooperation of distinct Rac-dependent pathways to stabilise E-cadherin adhesion

The precise mechanisms via which Rac1 is activated by cadherin junctions are not fully known. In keratinocytes Rac1 activation by cadherin junctions requires EGFR signalling, but how EGFR does so is unclear. To address which activator could mediate E-cadherin signalling to Rac1, we investigated EGFR...

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Détails bibliographiques
Publié dans:Cell Signal
Auteurs principaux: Erasmus, Jennifer C., Welsh, Natalie J., Braga, Vania M.M.
Format: Artigo
Langue:Inglês
Publié: Elsevier Science Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508347/
https://ncbi.nlm.nih.gov/pubmed/25957131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.04.014
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