Dual-Trait Selection for Ethanol Consumption and Withdrawal: Genetic and Transcriptional Network Effects

BACKGROUND: Data from C57BL/6J (B6) × DBA/2J (D2) F2 intercrosses (B6×D2 F2), standard and recombinant inbred strains, and heterogeneous stock mice indicate that a reciprocal (or inverse) genetic relationship exists between alcohol consumption and withdrawal severity. Furthermore, some genetic studi...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Metten, Pamela, Dan Iancu, Ovidiu, Spence, Stephanie E., Walter, Nicole A. R., Oberbeck, Denesa, Harrington, Christina A., Colville, Alexandre, McWeeney, Shannon, Phillips, Tamara J., Buck, Kari J., Crabbe, John C., Belknap, John K., Hitzemann, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500109/
https://ncbi.nlm.nih.gov/pubmed/25581648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12574
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