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The reverse operation of Na(+)/Cl(−)-coupled neurotransmitter transporters–why amphetamines take two to tango
Sodium-chloride coupled neurotransmitter transporters achieve reuptake of their physiological substrate by exploiting the pre-existing sodium-gradient across the cellular membrane. This terminates the action of previously released substrate in the synaptic cleft. However, a change of the transmembra...
Enregistré dans:
Publié dans: | J Neurochem |
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Auteurs principaux: | , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497806/ https://ncbi.nlm.nih.gov/pubmed/19891736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06474.x |
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