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The reverse operation of Na(+)/Cl(−)-coupled neurotransmitter transporters–why amphetamines take two to tango

Sodium-chloride coupled neurotransmitter transporters achieve reuptake of their physiological substrate by exploiting the pre-existing sodium-gradient across the cellular membrane. This terminates the action of previously released substrate in the synaptic cleft. However, a change of the transmembra...

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Détails bibliographiques
Publié dans:J Neurochem
Auteurs principaux: Sitte, Harald H., Freissmuth, Michael
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497806/
https://ncbi.nlm.nih.gov/pubmed/19891736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06474.x
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