Development of a Highly Stable, Nonaqueous Glucagon Formulation for Delivery via Infusion Pump Systems

BACKGROUND: Despite a vigorous research effort, to date, the development of systems that achieve glucagon stability in aqueous formulations (without reconstitution) has failed to produce any clinical candidates. We have developed a novel, nonaqueous glucagon formulation based on a biocompatible phar...

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Pubblicato in:J Diabetes Sci Technol
Autori principali: Newswanger, Brett, Ammons, Steve, Phadnis, Neelima, Ward, W. Kenneth, Castle, Jessica, Campbell, Robert W., Prestrelski, Steven J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2015
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Special Section: Glucagon Therapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495537/
https://ncbi.nlm.nih.gov/pubmed/25550410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1932296814565131
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