Comprehensive establishment and characterization of orthoxenograft mouse models of malignant peripheral nerve sheath tumors for personalized medicine

Malignant peripheral nerve sheath tumors (MPNSTs) are soft-tissue sarcomas that can arise either sporadically or in association with neurofibromatosis type 1 (NF1). These aggressive malignancies confer poor survival, with no effective therapy available. We present the generation and characterization...

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Publicat a:EMBO Mol Med
Autors principals: Castellsagué, Joan, Gel, Bernat, Fernández-Rodríguez, Juana, Llatjós, Roger, Blanco, Ignacio, Benavente, Yolanda, Pérez-Sidelnikova, Diana, García-del Muro, Javier, Viñals, Joan Maria, Vidal, August, Valdés-Mas, Rafael, Terribas, Ernest, López-Doriga, Adriana, Pujana, Miguel Angel, Capellá, Gabriel, Puente, Xose S, Serra, Eduard, Villanueva, Alberto, Lázaro, Conxi
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492820/
https://ncbi.nlm.nih.gov/pubmed/25810463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404430
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