Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies

Aims: Ectopic activation of tissue-specific genes accompanies malignant transformation in many cancers. Prolactin (PRL) aberrant activation in lung cancer was investigated here to highlight its value as a biomarker. Results: PRL is ectopically activated in a subset of very aggressive lung tumors, as...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antioxid Redox Signal
मुख्य लेखकों: Le Bescont, Aurore, Vitte, Anne-Laure, Debernardi, Alexandra, Curtet, Sandrine, Buchou, Thierry, Vayr, Jessica, de Reyniès, Aurélien, Ito, Akihiro, Guardiola, Philippe, Brambilla, Christian, Yoshida, Minoru, Brambilla, Elisabeth, Rousseaux, Sophie, Khochbin, Saadi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Mary Ann Liebert, Inc. 2015
विषय:
Forum Original Research CommunicationsHistone Deacetylases (S. Chiocca, Ed.)
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492736/
https://ncbi.nlm.nih.gov/pubmed/24512221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5581
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