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Seatbelts in CAR therapy: How Safe Are CARS?
T-cells genetically redirected with a chimeric antigen receptor (CAR) to recognize tumor antigens and kill tumor cells have been infused in several phase 1 clinical trials with success. Due to safety concerns related to on-target/off-tumor effects or cytokine release syndrome, however, strategies to...
Gardado en:
| Publicado en: | Pharmaceuticals (Basel) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491658/ https://ncbi.nlm.nih.gov/pubmed/26110321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph8020230 |
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