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The Reed-Sternberg cells of Hodgkin disease are clonal.

Relatively little progress has been made in understanding the nature of the Reed-Sternberg (RS) cell and its morphologic variants in Hodgkin disease (HD). This is primarily due to the fact that RS cells represent a minute subpopulation within HD lesions. To investigate the clonal origin of RS cells...

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Bibliographic Details
Main Authors: Inghirami, G, Macri, L, Rosati, S, Zhu, B Y, Yee, H T, Knowles, D M
Format: Artigo
Language:Inglês
Published: 1994
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC44913/
https://ncbi.nlm.nih.gov/pubmed/7937902
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