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Dysregulation of the Met pathway in non-small cell lung cancer: implications for drug targeting and resistance

The receptor tyrosine kinase, Met, orchestrates a complex signalling network that physiologically drives a programme of ‘invasive growth’. In cancer however, this process may be co-opted to promote proliferation, survival and metastasis of cancer cells. Met is thus a key therapeutic target, not leas...

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Publicat a:Transl Lung Cancer Res
Autors principals: Sacco, Joseph J., Clague, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483475/
https://ncbi.nlm.nih.gov/pubmed/26207212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2015.03.05
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