Positive predictive value of non-invasive prenatal screening for fetal chromosome disorders using cell-free DNA in maternal serum: independent clinical experience of a tertiary referral center

BACKGROUND: Non-invasive prenatal screening (NIPS) for fetal chromosome abnormalities using cell-free deoxyribonucleic acid (cfDNA) in maternal serum has significantly influenced prenatal diagnosis of fetal aneuploidies since becoming clinically available in the fall of 2011. High sensitivity and sp...

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Bibliographic Details
Published in:BMC Med
Main Authors: Neufeld-Kaiser, Whitney A., Cheng, Edith Y., Liu, Yajuan J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480508/
https://ncbi.nlm.nih.gov/pubmed/26033224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0374-8
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