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Differential effects of relaxin deficiency on vascular aging in arteries of male mice

Exogenous treatment with the naturally occurring peptide relaxin increases arterial compliance and reduces vascular stiffness. In contrast, relaxin deficiency reduces the passive compliance of small renal arteries through geometric and compositional vascular remodeling. The role of endogenous relaxi...

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Bibliographic Details
Published in:Age (Dordr)
Main Authors: Jelinic, Maria, Tare, Marianne, Conrad, Kirk P., Parry, Laura J.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480228/
https://ncbi.nlm.nih.gov/pubmed/26109313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-015-9803-z
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