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Differential effects of relaxin deficiency on vascular aging in arteries of male mice

Exogenous treatment with the naturally occurring peptide relaxin increases arterial compliance and reduces vascular stiffness. In contrast, relaxin deficiency reduces the passive compliance of small renal arteries through geometric and compositional vascular remodeling. The role of endogenous relaxi...

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Bibliografiske detaljer
Udgivet i:Age (Dordr)
Main Authors: Jelinic, Maria, Tare, Marianne, Conrad, Kirk P., Parry, Laura J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480228/
https://ncbi.nlm.nih.gov/pubmed/26109313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-015-9803-z
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