USP18 lack in microglia causes destructive interferonopathy of the mouse brain

Microglia are tissue macrophages of the central nervous system (CNS) that control tissue homeostasis. Microglia dysregulation is thought to be causal for a group of neuropsychiatric, neurodegenerative and neuroinflammatory diseases, called “microgliopathies”. However, how the intracellular stimulati...

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Detaylı Bibliyografya
Yayımlandı:EMBO J
Asıl Yazarlar: Goldmann, Tobias, Zeller, Nicolas, Raasch, Jenni, Kierdorf, Katrin, Frenzel, Kathrin, Ketscher, Lars, Basters, Anja, Staszewski, Ori, Brendecke, Stefanie M, Spiess, Alena, Tay, Tuan Leng, Kreutz, Clemens, Timmer, Jens, Mancini, Grazia MS, Blank, Thomas, Fritz, Günter, Biber, Knut, Lang, Roland, Malo, Danielle, Merkler, Doron, Heikenwälder, Mathias, Knobeloch, Klaus-Peter, Prinz, Marco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475397/
https://ncbi.nlm.nih.gov/pubmed/25896511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490791
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