Fibrogenic Cell Plasticity Blunts Tissue Regeneration and Aggravates Muscular Dystrophy

Preservation of cell identity is necessary for homeostasis of most adult tissues. This process is challenged every time a tissue undergoes regeneration after stress or injury. In the lethal Duchenne muscular dystrophy (DMD), skeletal muscle regenerative capacity declines gradually as fibrosis increa...

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Udgivet i:Stem Cell Reports
Main Authors: Pessina, Patrizia, Kharraz, Yacine, Jardí, Mercè, Fukada, So-ichiro, Serrano, Antonio L., Perdiguero, Eusebio, Muñoz-Cánoves, Pura
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472037/
https://ncbi.nlm.nih.gov/pubmed/25981413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.04.007
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