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EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival

Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus that can give rise to cancers of both B-cell and epithelial cell origin. In EBV-induced cancers of epithelial origin, including nasopharyngeal carcinomas (NPCs) and gastric carcinomas, the latent EBV genome expresses very high levels of a...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Kang, Dong, Skalsky, Rebecca L., Cullen, Bryan R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466530/
https://ncbi.nlm.nih.gov/pubmed/26070070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004979
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