Sodium Tanshinone IIA Sulfonate Ameliorates Bladder Fibrosis in a Rat Model of Partial Bladder Outlet Obstruction by Inhibiting the TGF-β/Smad Pathway Activation

Transforming growth factor (TGF)-β1 is known to play a pivotal role in a diverse range of biological systems including modulation of fibrosis in several organs. The precise role of TGF-β/Smad signaling in the progression of bladder fibrosis secondary to partial bladder outlet obstruction (PBOO) is y...

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Publicado en:PLoS One
Autores principales: Jiang, Xiaoxiao, Chen, Yaping, Zhu, Haitao, Wang, Bo, Qu, Ping, Chen, Renfu, Sun, Xiaoqing
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464658/
https://ncbi.nlm.nih.gov/pubmed/26061047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129655
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