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Overexpression of Lamin B Receptor Results in Impaired Skin Differentiation

Hutchinson-Gilford progeria syndrome (HGPS) is a rare segmental progeroid disorder commonly caused by a point mutation in the LMNA gene that results in the increased activation of an intra-exonic splice site and the production of a truncated lamin A protein, named progerin. In our previous work, ind...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sola Carvajal, Agustín, McKenna, Tomás, Wallén Arzt, Emelie, Eriksson, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459694/
https://ncbi.nlm.nih.gov/pubmed/26053873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128917
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