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Gamma-Carboxylation and Fragmentation of Osteocalcin in Human Serum Defined by Mass Spectrometry

Serum osteocalcin (Oc) concentration is a highly specific measure of bone turnover, but its circulating proteoform(s) have not been well defined. Based on immunological methods, the major forms are thought to be the intact polypeptide and a large N-terminal-mid molecule fragment for which there is n...

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Publicado en:Mol Cell Proteomics
Autores principales: Rehder, Douglas S., Gundberg, Caren M., Booth, Sarah L., Borges, Chad R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458719/
https://ncbi.nlm.nih.gov/pubmed/25855755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.047621
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