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A non-canonical function of Gβ as a subunit of E3 ligase in targeting GRK2 ubiquitylation
G protein-coupled receptors (GPCRs) comprise the largest family of cell-surface receptors, regulate a wide range of physiological processes, and are the major targets of pharmaceutical drugs. Canonical signaling from GPCRs is relayed to intracellular effector proteins by trimeric G proteins, compose...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Cell |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458238/ https://ncbi.nlm.nih.gov/pubmed/25982117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.04.017 |
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