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Selection on noise constrains variation in a eukaryotic promoter

Genetic variation segregating within a species reflects the combined activities of mutation, selection, and genetic drift. In the absence of selection, polymorphisms are expected to be a random subset of new mutations; thus, comparing the effects of polymorphisms and new mutations provides a test fo...

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Publicat a:Nature
Autors principals: Metzger, Brian P. H., Yuan, David C., Gruber, Jonathan D., Duveau, Fabien, Wittkopp, Patricia J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455047/
https://ncbi.nlm.nih.gov/pubmed/25778704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14244
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