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Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea

OBJECTIVE: Cytochrome P450 2B6 (CYP2B6) is involved in the metabolism of artemisinin drugs, a novel series of antimalarials. Our aim was to analyze the prevalence of the most commonly observed CYP2B6 alleles in malaria-endemic populations of West Africa (WA) and Papua New Guinea (PNG). METHODS: Usin...

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Bibliografiske detaljer
Udgivet i:Eur J Clin Pharmacol
Main Authors: Mehlotra, Rajeev K., Ziats, Mark N., Zimmerman, Peter A., Bockarie, Moses J.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450653/
https://ncbi.nlm.nih.gov/pubmed/16506047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-005-0092-9
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