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Prokinetic effects of large-dose lubiprostone on gastrointestinal transit in dogs and its mechanisms

Objective: To systemically explore effects of large dose of lubiprostone on gastrointestinal (GI) transit and contractions and its safety in dogs. Methods: 12 healthy dogs were studied. 6 dogs were operated to receive duodenal cannula and colon cannula and the other 6 dogs received gastric cannula....

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Detalles Bibliográficos
Publicado en:Am J Transl Res
Main Authors: Song, Jun, Yin, Jieyun, Xu, Xiaohong, Chen, Jiande
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448191/
https://ncbi.nlm.nih.gov/pubmed/26045891
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