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Insulin stimulates SGLT2-mediated tubular glucose absorption via oxidative stress generation
BACKGROUND: Ninety percent of glucose filtered by the glomerulus is reabsorbed by a sodium-glucose cotransporter 2 (SGLT2), which is expressed mainly on the apical membrane of renal proximal tubules. Since SGLT-2-mediated glucose reabsorption is enhanced under diabetic conditions, selective inhibiti...
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| Publié dans: | Diabetol Metab Syndr |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4447012/ https://ncbi.nlm.nih.gov/pubmed/26023321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-015-0044-1 |
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