Microarchitectural deterioration of cortical and trabecular bone: Differing effects of denosumab and alendronate

The intensity of bone remodeling is a critical determinant of the decay of cortical and trabecular microstructure after menopause. Denosumab suppresses remodeling more than alendronate, leading to greater gains in areal bone mineral density (aBMD). These greater gains may reflect differing effects o...

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Publicado en:J Bone Miner Res
Autores principales: Seeman, Ego, Delmas, Pierre D, Hanley, David A, Sellmeyer, Deborah, Cheung, Angela M, Shane, Elizabeth, Kearns, Ann, Thomas, Thierry, Boyd, Steven K, Boutroy, Stephanie, Bogado, Cesar, Majumdar, Sharmila, Fan, Michelle, Libanati, Cesar, Zanchetta, Jose
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445722/
https://ncbi.nlm.nih.gov/pubmed/20222106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.81
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