Microarchitectural deterioration of cortical and trabecular bone: Differing effects of denosumab and alendronate

The intensity of bone remodeling is a critical determinant of the decay of cortical and trabecular microstructure after menopause. Denosumab suppresses remodeling more than alendronate, leading to greater gains in areal bone mineral density (aBMD). These greater gains may reflect differing effects o...

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Bibliographic Details
Published in:J Bone Miner Res
Main Authors: Seeman, Ego, Delmas, Pierre D, Hanley, David A, Sellmeyer, Deborah, Cheung, Angela M, Shane, Elizabeth, Kearns, Ann, Thomas, Thierry, Boyd, Steven K, Boutroy, Stephanie, Bogado, Cesar, Majumdar, Sharmila, Fan, Michelle, Libanati, Cesar, Zanchetta, Jose
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2010
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445722/
https://ncbi.nlm.nih.gov/pubmed/20222106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.81
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