Microarchitectural deterioration of cortical and trabecular bone: Differing effects of denosumab and alendronate

The intensity of bone remodeling is a critical determinant of the decay of cortical and trabecular microstructure after menopause. Denosumab suppresses remodeling more than alendronate, leading to greater gains in areal bone mineral density (aBMD). These greater gains may reflect differing effects o...

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Vydáno v:J Bone Miner Res
Hlavní autoři: Seeman, Ego, Delmas, Pierre D, Hanley, David A, Sellmeyer, Deborah, Cheung, Angela M, Shane, Elizabeth, Kearns, Ann, Thomas, Thierry, Boyd, Steven K, Boutroy, Stephanie, Bogado, Cesar, Majumdar, Sharmila, Fan, Michelle, Libanati, Cesar, Zanchetta, Jose
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2010
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445722/
https://ncbi.nlm.nih.gov/pubmed/20222106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.81
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