Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?

OBJECTIVES: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this hypothesis-generating, secondary analysis was to identify candidate single nucleotide polymorphi...

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Bibliografiske detaljer
Udgivet i:BMJ Open
Main Authors: Currow, David C, Quinn, Stephen, Ekstrom, Magnus, Kaasa, Stein, Johnson, Miriam J, Somogyi, Andrew A, Klepstad, Päl
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2015
Fag:
Palliative Care
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431168/
https://ncbi.nlm.nih.gov/pubmed/25948405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-006818
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