Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat.

Heme proteins such as myoglobin or hemoglobin, when released into the extracellular space, can instigate tissue toxicity. Myoglobin is directly implicated in the pathogenesis of renal failure in rhabdomyolysis. In the glycerol model of this syndrome, we demonstrate that the kidney responds to such i...

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Bibliographic Details
Main Authors: Nath, K A, Balla, G, Vercellotti, G M, Balla, J, Jacob, H S, Levitt, M D, Rosenberg, M E
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC443091/
https://ncbi.nlm.nih.gov/pubmed/1634613
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