Heat fixation inactivates viral and bacterial pathogens and is compatible with downstream MALDI mass spectrometry tissue imaging

BACKGROUND: Tissue samples should be fixed and permanently stabilized as soon as possible ex-vivo to avoid variations in proteomic content. Tissues collected from studies involving infectious microorganisms, must face the additional challenge of pathogen inactivation before downstream proteomic anal...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Cazares, Lisa H, Van Tongeren, Sean A, Costantino, Julie, Kenny, Tara, Garza, Nicole L, Donnelly, Ginger, Lane, Douglas, Panchal, Rekha G, Bavari, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429342/
https://ncbi.nlm.nih.gov/pubmed/25966989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-015-0431-7
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