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Adenosine signaling promotes hematopoietic stem and progenitor cell emergence
Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The molecular mechanisms that initiate and regulate EHT remain poorly understood. Here, we show that adenosine signaling regulates hematopoietic stem and progenitor cell (HSPC) devel...
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Pubblicato in: | J Exp Med |
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Autori principali: | , , , , , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
The Rockefeller University Press
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419349/ https://ncbi.nlm.nih.gov/pubmed/25870200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141528 |
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