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Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The molecular mechanisms that initiate and regulate EHT remain poorly understood. Here, we show that adenosine signaling regulates hematopoietic stem and progenitor cell (HSPC) devel...

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Pubblicato in:J Exp Med
Autori principali: Jing, Lili, Tamplin, Owen J., Chen, Michael J., Deng, Qing, Patterson, Shenia, Kim, Peter G., Durand, Ellen M., McNeil, Ashley, Green, Julie M., Matsuura, Shinobu, Ablain, Julien, Brandt, Margot K., Schlaeger, Thorsten M., Huttenlocher, Anna, Daley, George Q., Ravid, Katya, Zon, Leonard I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419349/
https://ncbi.nlm.nih.gov/pubmed/25870200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141528
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