Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The molecular mechanisms that initiate and regulate EHT remain poorly understood. Here, we show that adenosine signaling regulates hematopoietic stem and progenitor cell (HSPC) devel...

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Publicado en:J Exp Med
Main Authors: Jing, Lili, Tamplin, Owen J., Chen, Michael J., Deng, Qing, Patterson, Shenia, Kim, Peter G., Durand, Ellen M., McNeil, Ashley, Green, Julie M., Matsuura, Shinobu, Ablain, Julien, Brandt, Margot K., Schlaeger, Thorsten M., Huttenlocher, Anna, Daley, George Q., Ravid, Katya, Zon, Leonard I.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419349/
https://ncbi.nlm.nih.gov/pubmed/25870200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141528
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