Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The molecular mechanisms that initiate and regulate EHT remain poorly understood. Here, we show that adenosine signaling regulates hematopoietic stem and progenitor cell (HSPC) devel...

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Udgivet i:J Exp Med
Main Authors: Jing, Lili, Tamplin, Owen J., Chen, Michael J., Deng, Qing, Patterson, Shenia, Kim, Peter G., Durand, Ellen M., McNeil, Ashley, Green, Julie M., Matsuura, Shinobu, Ablain, Julien, Brandt, Margot K., Schlaeger, Thorsten M., Huttenlocher, Anna, Daley, George Q., Ravid, Katya, Zon, Leonard I.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419349/
https://ncbi.nlm.nih.gov/pubmed/25870200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141528
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