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MPTP’s Pathway of Toxicity Indicates Central Role of Transcription Factor SP1
Deriving a Pathway of Toxicity from transcriptomic data remains a challenging task. We explore the use of weighted gene correlation network analysis (WGCNA) to extract an initial network from a small microarray study of MPTP toxicity in mice. Five modules were statistically significant; each module...
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| Udgivet i: | Arch Toxicol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4415653/ https://ncbi.nlm.nih.gov/pubmed/25851821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-015-1509-6 |
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