Construction, Expression, and Characterization of a Recombinant Immunotoxin Targeting EpCAM

Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein overexpressed in human epithelioma but with relatively low expression in normal epithelial tissues. To exploit this differential expression pattern for targeted cancer therapy, an EpCAM-targeted immunotoxin was develope...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mediators Inflamm
Autori principali: Lv, Minghua, Qiu, Feng, Li, Tingting, Sun, Yuanjie, Zhang, Chunmei, Zhu, Ping, Qi, Xiaokun, Wan, Jun, Yang, Kun, Zhang, Kui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415474/
https://ncbi.nlm.nih.gov/pubmed/25960617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/460264
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